锘?!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Transitional//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-transitional.dtd"> 绮惧噯鍖荤枟锛屼釜浣撳寲鐢ㄨ嵂
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          瀵艰█锛?/span>闅忕潃EGFR-TKI绫婚澏鍚戣嵂鐗╃殑鍑虹幇锛屽浣曞埄鐢ㄩ澏鍚戣嵂鐗╁埗瀹氬嚭鏈€浣虫不鐤楁柟妗堬紝鏄墍鏈変复搴婂尰鐢熼潰涓寸殑鍏卞悓鎸戞垬锛屼篃鎴愪负鐮旂┒棰嗗煙鐨勪竴澶х儹鐐广€?/p>

          绮惧噯鍖荤枟锛屼釜浣撳寲鐢ㄨ嵂

          闅忕潃EGFR-TKI绫婚澏鍚戣嵂鐗╃殑鍑虹幇锛屽浣曞埄鐢ㄩ澏鍚戣嵂鐗╁埗瀹氬嚭鏈€浣虫不鐤楁柟妗堬紝鏄墍鏈変复搴婂尰鐢熼潰涓寸殑鍏卞悓鎸戞垬锛屼篃鎴愪负鐮旂┒棰嗗煙鐨勪竴澶х儹鐐广€傛偅鑰呭笇鏈涗簡瑙o紝浣曠鑽墿瀵硅嚜浣撴湁鏁堬紝浣曟椂澶辨晥浜х敓鍓綔鐢紝鑽晥鎸佺画澶氫箙锛涢殢鐫€浜虹被鍩哄洜缁勭殑瑙e瘑锛屼粠姝や釜浣撳寲鐢ㄨ嵂閫愭瀹炵幇銆傚埄鐢ㄥ厛杩涚殑鏍搁吀缁濆瀹氶噺鐨勬妧鏈紝瀵逛笉鍚屼釜浣撶殑鑽墿鐩稿叧鍩哄洜杩涜妫€娴嬶紝涓村簥鍖荤敓鍙牴鎹偅鑰呯殑鍩哄洜鍨嬭祫鏂欏疄鏂界粰鑽柟妗堬紝鎻愰珮鑽墿瀵逛釜浣撶殑鐤楁晥璇勪及锛岄檷浣庤嵂鐗╃殑姣掑壇鍙嶅簲锛屽悓鏃跺噺杞绘偅鑰呯殑鐥涜嫤鍜岀粡娴庤礋鎷呫€?/font> NaicaTM crystal鍏ㄨ嚜鍔ㄥ井婊磋姱鐗囨暟瀛桺CR浠郴缁熼噰鐢ㄥ垱鏂癉roplets in chip寰淮鑺墖寮忔妧鏈紝鍗崇О涓哄井婊磋姱鐗囨暟瀛桺CR绯荤粺銆傛簮鑷硶鍥絊tilla鎶€鏈垱鏂扮敓鐗╁叕鍙革紝鍦ㄨ繃鍘荤煭鐭?骞翠腑杩炵画澧為暱瓒呰繃100锛呯殑鍏徃涓氱哗銆侰rystal寰淮鑺墖鏁板瓧PCR鎶€鏈紝鑾峰緱缇庡浗MIT鍒涙柊濂栵紝娉曞浗绉戞妧鍒涙柊濂栵紝绛夎澶氬椤癸紝璇ヤ骇鍝佸凡琚叏鐞?0澶氫釜瀹為獙瀹ら噰绾冲拰璁ゅ彲锛屽叾涓寘鎷娲叉潈濞佺殑5澶х檶鐥囦腑蹇冨拰鍏ㄧ悆鐭ュ悕8涓瘖鏂叕鍙革紱灏卞湪3鏈?8鍙稴tilla鎶€鏈叕鍙歌幏寰楀叏娆ф床鏈€澶х殑澶у闄勫睘鍖婚櫌鏈烘瀯AP-HP鐨勬巿浜堜腑鏍囧叕绀猴紝鍦ㄤ粖鍚庣殑4骞村唴浣滀负鍞竴渚涘簲鍟嗕负璇ユ満鏋勪笅灞炵殑39瀹跺尰闄㈡彁渚汵aicaTM crystal寰淮鑺墖鏁板瓧PCR鎶€鏈骇鍝併€?/span>

          浜у搧鎸囧崡

          NaicaTM crystal鍏ㄨ嚜鍔ㄥ井婊磋姱鐗囨暟瀛桺CR浠郴缁?/p>

          • Crystal寰淮鑺墖鏁板瓧PCR鎶€鏈紩棰嗕笅涓€浠f牳閰哥粷瀵瑰畾閲?/li>
          • 鍙交鏉炬帉鎺х殑Crystal鍏ㄨ嚜鍔ㄥ井婊磋姱鐗囨暟瀛桺CR浠郴缁燂紝鍏ㄦ柊鐨勭敤鎴蜂綋楠?/li>
          • Sapphire鑺墖锛岄《灏栫殑寰祦鎺у伐涓氳璁?/li>
          • 绠€鍗曟槗鐢細鏁村悎浼樺寲瀹為獙娴佺▼锛?涓崐灏忔椂蹇€熷畬鎴愶紝浠呴渶涓€姝ユ墜鍔ㄦ搷浣?/li>
          • 鏇寸洿瑙傜殑缁熻瀛﹀垎鏋愯蒋浠讹細绠€鍗曚笁閮ㄥ嵆鍙幏寰楁偍鐨勫疄楠岀粨鏋?/li>

          搴旂敤棰嗗煙

          Crystal寰淮鑺墖鏁板瓧PCR鎶€鏈弧瓒虫偍鐨勬牳閰哥粷瀵瑰畾閲忕殑
          搴旂敤闇€姹?/p>

          • 閫傜敤浜庡绉嶆娴嬬被鍨嬪垎鏋?/li>
          • Liqid Biopsy 娑蹭綋娲绘
          • Tumor Prognositic 鑲跨槫棰勫悗
          • Tumor Monitoring 鑲跨槫鐩戞帶

          瀹為獙妗堜緥

          妗堜緥涓€锛?br/>Naica鈩?crystal鍏ㄨ嚜鍔ㄥ井婊磋姱鐗囨暟瀛桺CR浠郴缁熷閲嶆娴?/P>

          • 閫氬父鍦ㄧ敓鐗╂牱鏈暟閲忔湁闄愮殑鎯呭喌涓嬶紝鍗曟瀹為獙鑾峰緱瓒冲澶氱殑淇℃伅瀵逛簬鐮旂┒浜哄憳鍜岃瘖鏂汉鍛樿嚦鍏抽噸瑕併€侼aica鈩?crystal鍏ㄨ嚜鍔ㄥ井婊磋姱鐗囨暟瀛桺CR浠郴缁熷疄鐜颁簡鍗曟瀹為獙涓悓鏃舵娴嬪拰瀹氶噺澶氶噸鐢熺墿鏍囧織鐗╋紝骞剁‘淇濇暟鎹簿鍑嗗害鍜屽彲淇″害锛岄€氳繃3 涓笉鍚岀殑鑽у厜閫氶亾锛岄潪甯告槑纭湴鍖哄垎闈舵爣浣嶇偣銆傝繖绉嶇畝鍗曞揩閫熺殑鎶€鏈钩鍙拌兘澶熷吋瀹瑰绉嶈崸鍏夋煋鏂欑粍鍚堬紝澶уぇ鍦版墿灞曚簡瀹為獙璁捐鐨勫彲鑳芥€с€?/li>
          • 鍦∟SCLC锛堥潪灏忕粏鑳炶偤鐧岋級娌荤枟涓紝EGFR锛堣〃鐨敓闀垮洜瀛愬彈浣擄級鏄噸瑕佺殑鑽墿浣滅敤闈剁偣銆侲GFR 娲诲寲绐佸彉浣嶇偣锛屽L858R 鍜孡861Q鐢ㄤ簬棰勬祴TKIs锛堥叒姘ㄩ吀婵€閰舵姂鍒跺墏锛夎嵂鐗╄嵂鏁堬紝鍚屾椂EGFR T790M绐佸彉鐢ㄤ簬涓嬩竴浠KIs 鑽墿鑰愯嵂棰勬祴銆?/li>
          • 涓鸿兘澶熷湪鍗曟瀹為獙涓瘎浼癟KIs 鑽墿鍙嶅簲锛屽湪Naica鈩?crystal鍏ㄨ嚜鍔ㄥ井婊磋姱鐗囨暟瀛桺CR浠郴缁熶笂杩涜鐨勫閲嶆暟瀛桺CR 瀹為獙锛屽疄鐜颁簡鍚屾椂妫€娴婨GFR L858R銆丩861Q銆乀790M 鍜岄噹鐢熷瀷EGFR銆傚湪閲庣敓鍨嬭儗鏅笅锛屽彲浠ユ垚鍔熷苟鍑嗙‘鍦版娴嬪埌缁堟祿搴︿綆鑷?.25 copies/碌L 鐨勭獊鍙橈紝瀵瑰簲鐨勭獊鍙樻娴嬮檺涓?.05% (Figure A锛孊锛孋)銆?/li>

          妗堜緥浜岋細
          鍩轰簬EvaGreen鏂规硶鐨刢rystal鏁板瓧PCR缁濆瀹氶噺妫€娴?/p>

          • EvaGreen 鏄竴绉嶆棤鑷寸獊鍙樻€с€佹棤缁嗚優姣掓€х殑DNA 缁撳悎鏌撴枡锛屽弽搴斾綋绯讳腑娓哥鐨凟vaGreen 鏌撴枡涓嶅彂鍑鸿崸鍏変俊鍙凤紝浣嗕笌鍙岄摼DNA锛坉sDNA锛夌粨鍚堝悗浼氬彂鍑哄緢寮虹殑鑽у厜銆?/li>
          • Naica鈩?crystal鍏ㄨ嚜鍔ㄥ井婊磋姱鐗囨暟瀛桺CR浠郴缁熷彲鍏煎EvaGreen鏌撴枡杩涜鐨勬暟瀛桺CR 瀹為獙鍒嗘瀽銆備娇鐢ㄦ娴嬪弬姣旇崸鍏夛紙鑽у厜绱犻挔鐩愶級鐩稿悓鐨勬护鍏夌墖鍙繘琛孍vaGreen 鏌撴枡鑽у厜淇″彿鐨勬娴嬨€?
          • Naica鈩?crystal鍏ㄨ嚜鍔ㄥ井婊磋姱鐗囨暟瀛桺CR浠郴缁熶娇鐢‥vaGreen鍙互閫氳繃浣跨敤绠€鍗曠殑寮曠墿鏉ュ疄鐜伴澏鏍囩粷瀵瑰畾閲忋€備娇鐢ㄦ垜浠殑Sapphire鑺墖銆佸熀浜嶦vaGreen鐨勬柟娉曞彲妫€娴嬩綆鑷?.2 copies/碌L銆?

          鏂囩尞璧勬枡

          • October 2016, Three-color crystal digital PCR (Biomelocular Detection and Quantification )
          • August 2017, Crystal digital droplet PCR for detection and quantification of circulating EGFR sensitizing and resistance mutations in advanced nonsmall cell lung cancer (Plos One)
          • 鏇村鐨勬枃绔犱俊鎭紝鍙櫥褰曟垜浠綉绔?http://stillatechnologies.com 鎴?http://www.cycloudbio.com

          浼佷笟璇?/span>

          鍖椾含娣辫摑浜戠敓鐗╃鎶€鏈夐檺鍏徃

          • 鑷村姏浜庝负鐢ㄦ埛鎻愪緵鏂板瀷鐢熷懡绉戝鐮旂┒浠櫒鍜屽垎鏋愪骇鍝佷互鍙婁紭鍖栫殑鏁翠綋搴旂敤瑙e喅鏂规銆? 娣辫摑浜戠敓鐗╅厤澶囩潃涓撲笟鐨勬妧鏈敮鎸佸拰搴旂敤鏀寔锛屼緷鎵樺浗闄呴鍏堢殑鐢熷懡绉戝浜у搧鍜岃В鍐虫柟妗堬紝涓撴敞涓虹敤鎴锋彁渚涘垎鏋愪骇鍝佸拰瀹屽杽鐨勫敭鍓嶅挩璇㈠拰鍞悗鏈嶅姟銆?/li>
          • 娉曞浗Stilla Technologies
            娉曞浗Stilla Technologies鍏徃浣嶄簬娉曞浗宸撮粠Villejuif鐢熺墿鍥紝鎴愮珛浜?013
            骞达紝涓撴敞浜庡紑鍙戞柊涓€浠c€侀珮鍒嗚鲸鐜囩殑鍩哄洜妫€娴嬪伐鍏凤紝鍏朵骇鍝丯aica鈩?Crystal寰淮鏁板瓧PCR绯荤粺鏄競鍦轰笂鎿嶄綔鏈€绠€渚裤€佽€屼笖鏄敮涓€涓€娆惧悓鏃跺疄
            鐜颁笁鑹叉娴嬬殑鏁板瓧PCR绯荤粺锛屼负鐢熺墿鐮旂┒浜哄憳鎻愪緵蹇嵎銆佺簿鍑嗙殑鏍搁吀缁?br /> 瀵瑰畾閲忓伐鍏枫€?
          • 鎶€鏈ず鑼冧腑蹇冨湴鍧€锛?/strong>
            鍖椾含浜﹀簞缁忔祹寮€鍙戝尯缁忔捣鍥涜矾 BOX浼佷笟姹?5鍙烽櫌2鍙锋ゼ3灞?/li>
          • 鑱旂郴鐢佃瘽锛?/strong>010-57256059
          • 閭锛?/strong>info@cycloudbio.com
          • 缃戝潃锛?/strong>www.cycloudbio.com

          • 瀹樻柟鍏紬鍙?/li>
          • 瀹樻柟寰崥

          浜掑姩鍖?/span>

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